Later analyses of X chromosome and autosomal DNA continued to find sites with deep coalescence times inconsistent with a single origin of modern humans, diversity patterns inconsistent with a recent expansion from Africa, or both. For example, analyses of a region of RRM2P4 (ribonucleotide reductase M2 subunit pseudogene 4) showed a coalescence time of about 2 Mya, with a clear root in Asia, while the MAPT locus at 17q21.31 is split into two deep genetic lineages, one of which is common in and largely confined to the present European population, suggesting inheritance from Neanderthals. In the case of the Microcephalin D allele, evidence for rapid recent expansion indicated introgression from an archaic population.
In a 2005 review and analysis of the genetic lineages of 25 chromosomal regions, Alan Templeton found evidence of more than 34 occurrences of gene flow between Africa and Eurasia. Of these occurrences, 19 were associated with continuous restricted gene exchange through at least 1.46 million years ago; only 5 were associated with a recent expansion from Africa to Eurasia. Three were associated with the original expansion of Homo erectus out of Africa around 2 million years ago, 7 with an intermediate expansion out of Africa at a date consistent with the expansion of Acheulean tool technology, and a few others with other gene flows such as an expansion out of Eurasia and back into Africa subsequent to the most recent expansion out of Africa. Templeton rejected a hypothesis of recent African replacement with greater than 99% certainty (p < 10−17).
Okazuje sie,ze nuclear DNA odrzuca niemal na 100% teorie Out of Africa.
Oczywiscie ta czesc encyklopedii nie zostala przetlumaczona na polski by w Polsce w dalszym ciagu mogl funcjonowac mit Out of Africa.